Decreased Stroke Volume and Venous Return in School Children with Postural Tachycardia Syndrome

In postural tachycardia syndrome (POTS), a subtype of orthostatic intolerance, the changes in hemodynamics due to are poorly understood. We speculated that inappropriate venous return, which may occur upright position patients with school-aged POTS, could be detected by echocardiography. Our prospective study was conducted 100 POTS (45 boys and 55 girls), aged 13.1 ± 1.5 years 52 age- sex-matched healthy subjects (control). Echocardiography performed supine sitting positions. Cardiac parameters [stroke volume index, cardiac heart rate, maximum inferior vena cava diameter (max IVC)] were evaluated addition pulse pressure. Unlike control subjects, demonstrated decreased stroke index (P = 0.02) max IVC < 0.01) irrespective posture. The rates change did not differ between groups. enrolled divided into two subgroups [dilatation (n 57) contraction 43)] based on whether rate less than zero or not. group showed significantly higher dilatation respect posture 0.03), indicating poor response peripheral vessels lower limbs only group. conclusion, echocardiographic assessment return POTS. indicate an underlying pathophysiology